| Title (priority date): |
| Reference: |
1-32748/FMI |
| Inventors: |
Badache, Hynes and Schick |
| Description: |
The inventors discovered that activation of Stat3 to moderate levels was sufficient to repress cell proliferation, by slowing down cell transit through the cell cycle. Furthermore, enhanced and prolonged Stat3 activity led to cell cycle arrest and apoptosis. |
| Applications: |
Methods of identifying agents effective in modulating Stat3-dependent cell proliferation. |
| Status: |
Pending EP, JP and US |
| Opportunity: |
Exclusive or non exclusive license available |
| Publications: |
Schick et al., J Biol Chem. 2004 Sep 10;279(37):38787-96 |
| Contact: |
Dr. Nicolas Favre, tel: +41 61 6978382, e-mail: nicolas.favre@fmi.ch |
| PCT File: |
WO04042406 |
