| Title (priority date): |
| Reference: |
1-31255/FMI |
| Inventors: |
Altrogge and Monard |
| Description: |
The invention provides a simple, yet sensitive method for identifying PAR cleaving molecules by detecting a released reporter molecule. The detection of released reporter molecule allows for the quantitative and sensitive detection of PAR cleaving molecules. |
| Applications: |
Assays amenable to high through-put technologies allowing the identification of agonists or antagonists based on their ability to cleave a PAR cleavage peptide. The assays have the advantage over prior art methods in that they provide a positive reading, are highly sensitive and provide reliable, quantifiable measurements. |
| Status: |
Granted EP (1238283) and US (7029877). Validated in AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, NL, PT, SE and TR. |
| Opportunity: |
Exclusive or non exclusive license available |
| Publications: |
Altrogge et al., Anal Biochem. 2000 Jan 1;277(1):33-45. |
| Contact: |
Dr. Nicolas Favre, tel: +41 61 6978382, e-mail: nicolas.favre@fmi.ch |
| PCT File: |
WO0144496 |
