| |
| DIRK SCHÜBELER |
| Propagation and dynamics of epigenetic states |
 |
| While it is apparent that eukaryotic gene activation occurs in the context of chromatin, the precise nature of "chromatin structure" associated with gene activation and silencing is not clear. A variety of measurable characteristics of a gene locus, such as covalent histone modifications, DNA methylation and the timing of DNA replication have been shown to correlate with transcriptional activity and are presumed to regulate gene expression. Our research is aimed at further understanding, at the level of individual gene loci and genome-wide, how these nuclear events influence the expression phenotype in higher eukaryotes and how they are propagated during cell division. |
| |
For further information, please contact
Administrative Assistant Keri Jane Shilling
(+41 61 6976651) |
| |
To contact FMI members directly, click
here for the FMI Directory. |
| |
|
|
|
|
